Successful Treatment of Balamuthia mandrillaris Amoebic Infection with Extensive Neurological and Cutaneous Involvement

Granulomatous amoebic encephalitis caused by Balamuthia mandrillaris is an uncommon infection for which there is no optimal therapy. We describe a young, female patient who presented with extensive cutaneous and neurological involvement and who recovered after receiving prolonged treatment with miltefosine, fluconazole, and albendazole.