Journal
CLINICAL INFECTIOUS DISEASES
Volume 50, Issue 9, Pages 1252-1255Publisher
OXFORD UNIV PRESS INC
DOI: 10.1086/651605
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Funding
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [ZIAAI001113] Funding Source: NIH RePORTER
- Intramural NIH HHS [Z99 AI999999] Funding Source: Medline
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Pandemic 2009 H1N1 virus isolates containing the neuraminidase inhibitor resistance mutation H275Y have been reported. We describe rapid selection for the H275Y resistance mutation during therapy in 2 immunocompromised individuals at 9 and 14 days of therapy, as well as the first described case of clinically significant resistance to peramivir.
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