Journal
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
Volume 16, Issue 6, Pages 783-793Publisher
WILEY
DOI: 10.1111/cid.12052
Keywords
DNA analysis; microbiota; peri-implantitis
Categories
Funding
- University of Kristianstad Sweden
- University of Bern, Switzerland
Ask authors/readers for more resources
BackgroundInformation on the microbiota in peri-implantitis is limited. We hypothesized that neither gender nor a history of periodontitis/smoking or the microbiota at implants differ by implant status. Materials and MethodsBaseline microbiological samples collected at one implant in each of 166 participants with peri-implantitis and from 47 individuals with a healthy implant were collected and analyzed by DNA-DNA checkerboard hybridization (78 species). Clinical and radiographic data defined implant status. ResultsNineteen bacterial species were found at higher counts from implants with peri-implantitis including Aggregatibacter actinomycetemcomitans, Campylobacter gracilis, Campylobacter rectus, Campylobacter showae, Helicobacter pylori, Haemophilus influenzae, Porphyromonas gingivalis, Staphylococcus aureus, Staphylococcus anaerobius, Streptococcus intermedius, Streptococcus mitis, Tannerella forsythia, Treponema denticola, and Treponema socranskii (p<.001). Receiver operating characteristic curve analysis identified T.forsythia, P.gingivalis, T.socranskii, Staph.aureus, Staph.anaerobius, Strep.intermedius, and Strep.mitis in peri-implantitis comprising 30% of the total microbiota. When adjusted for gender (not significant [NS]), smoking status (NS), older age (p=.003), periodontitis history (p<.01), and T.forsythia (likelihood ratio 3.6, 95% confidence interval 1.4, 9.1, p=.007) were associated with peri-implantitis. ConclusionA cluster of bacteria including T.forsythia and Staph.aureus are associated with peri-implantitis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available