4.8 Article

Facile Enzymatic Synthesis of Ketoses

Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 54, Issue 43, Pages 12654-12658

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201505714

Keywords

enzymatic synthesis; ketoses; one-pot reactions; phosphorylation; synthetic methods

Funding

  1. National Institute of Health [R01GM085267]
  2. National Basic Research(973) Program of China [2012CB822102]
  3. Chinese Ministry of Education [313033]

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Studies of rare ketoses have been hampered by a lack of efficient preparation methods. A convenient, efficient, and cost-effective platform for the facile synthesis of ketoses is described. This method enables the preparation of difficult-to-access ketopentoses and ketohexoses from common and inexpensive starting materials with high yield and purity and without the need for a tedious isomer separation step.

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