4.4 Article

Hyperinsulinemia acutely increases serum macrophage inhibitory cytokine-1 concentration in anorexia nervosa and obesity

Journal

CLINICAL ENDOCRINOLOGY
Volume 76, Issue 1, Pages 46-50

Publisher

WILEY
DOI: 10.1111/j.1365-2265.2011.04139.x

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Funding

  1. Medical University of Bialystok, Poland [3-50706, 93-50945]

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Context Macrophage inhibitory cytokine-1 (MIC-1) plays a role in the regulation of cellular responses to stress signals and inflammation. MIC-1 has also been implicated in mediation of tumour-induced anorexia and weight loss. Increased serum concentrations of MIC-1 were found in patients with anorexia nervosa (AN), obesity and type 2 diabetes.

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