Journal
CLINICAL EEG AND NEUROSCIENCE
Volume 40, Issue 4, Pages 239-244Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/155005940904000406
Keywords
Autism; Electroencephalography; Psychiatry; Sleep EEG; Spikes, Inter-ictal
Funding
- Department of Psychiatry and Behavioral Neurosciences at Wayne State University, Detroit, Michigan
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The current view of the psychiatric significance of inter-ictal spike discharges (IIS) in nonepileptic, psychiatric patients is that the discharges are incidental and are of no clinical significance. Hence, despite a voluminous literature suggestive that such discharges may have clinical relevance, electroencephalograms are hardly ever recorded in nonepileptic psychiatric patients. This literature is briefly summarized, and one detailed example of a disorder (i.e., autistic spectrum disorders) where such discharges are particularly common is provided. The argument is made that this is an area of psychiatry that is under-investigated and that research devoted to elucidating the mechanisms of development of IIS, their possible clinical relevance, and the role of anticonvulsants in managing such patients, could be very profitable.
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