4.7 Editorial Material

Prostate Cancer SubtyPINg BiomarKers and Outcome: Is Clarity EmERGing?

Journal

CLINICAL CANCER RESEARCH
Volume 20, Issue 18, Pages 4733-4736

Publisher

AMER ASSOC CANCER RESEARCH
DOI: 10.1158/1078-0432.CCR-14-0818

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Funding

  1. NCI NIH HHS [R01 CA183857, R01-CA-183857-01] Funding Source: Medline

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Molecular prostate cancer subtypes have been proposed on the basis of mutually exclusive SPINK1 and ERG overexpression, with conflicting reports on their prognostic ability. Flavin and colleagues report that SPINK1 is neither prognostic nor absolutely mutually exclusive with ERG, raising important questions about prostate cancer molecular subtyping and prognostic biomarker evaluation. (C)2014 AACR.

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