Journal
CLINICAL CANCER RESEARCH
Volume 18, Issue 10, Pages 2723-2725Publisher
AMER ASSOC CANCER RESEARCH
DOI: 10.1158/1078-0432.CCR-12-0694
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- Canadian Cancer Society [2011-700625]
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Laboratory models show antineoplastic activity of metformin under certain conditions, and pharmacoepidemiologic studies have reported reduced cancer burden among diabetics taking metformin. Therefore, the hypothesis that metformin has antineoplastic activity is receiving increasing attention. However, gaps in knowledge must be addressed before metformin can be repurposed for oncologic indications. Clin Cancer Res; 18(10); 2723-5. (C)2012 AACR.
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