4.7 Editorial Material

Location, Location, Location-Makes All the Difference for Hypoxia in Lung Tumors

Journal

CLINICAL CANCER RESEARCH
Volume 16, Issue 19, Pages 4685-4687

Publisher

AMER ASSOC CANCER RESEARCH
DOI: 10.1158/1078-0432.CCR-10-2004

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Funding

  1. NCI NIH HHS [R01 CA094214] Funding Source: Medline
  2. NATIONAL CANCER INSTITUTE [R01CA094214] Funding Source: NIH RePORTER

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Hypoxia is a clinically important component of the tumor microenvironment because it adversely affects progression, metastasis, response to chemoradiation therapy, and overall patient survival. Here, we describe how different animal tumor models of lung cancer can yield surprisingly different hypoxic profiles. Clin Cancer Res; 16(19); 4685-7. (C) 2010 AACR.

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