Journal
CLINICAL BREAST CANCER
Volume 10, Issue 3, Pages 209-216Publisher
CIG MEDIA GROUP, LP
DOI: 10.3816/CBC.2010.n.028
Keywords
CA 15-3; CA 27.29; Cytokeratins; Disseminated tumor cells; EpCAM; MUC1
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Most deaths from breast cancer are from metastatic disease. Tests that predict an individual's risk of developing metastatic disease could be useful. There is growing evidence that circulating tumor cells (CTC) could help predict recurrence and effectiveness of therapy. However, there are unresolved issues with CTC detection methods and their implementation in the community. The utility of CTC testing in the management of breast cancer is unclear based on current studies. This article reviews the role of CTC testing in the management of early and metastatic breast cancer.
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