Journal
CLINICAL BREAST CANCER
Volume 8, Issue 3, Pages 285-286Publisher
CIG MEDIA GROUP, LP
DOI: 10.3816/CBC.2008.n.034
Keywords
HER2; lymphadenopathy; petechial rash; tamoxifen
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We report a case of severe thrombocytopenia related to adjuvant trastuzumab use. Less than 24 hours after administration of her first dose of single-agent trastuzumab, the patient was admitted to the hospital with a platelet count of 2 x 10(9)/L. Trastuzumab is being increasingly used and, to our knowledge, severe thrombocytopenia has not yet been reported as an adverse event. This case highlights a serious and potentially life-threatening complication with the use of single-agent trastuzumab.
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