4.5 Article

Serum Retinol-Binding Protein 4 (RBP4) and retinol in a cohort of borderline obese women with and without gestational diabetes

Journal

CLINICAL BIOCHEMISTRY
Volume 43, Issue 3, Pages 320-323

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.clinbiochem.2009.10.013

Keywords

Retinol-Binding Protein 4 (RBP4); Retinol; Gestational diabetes; BMI; Obesity

Funding

  1. USDA [2006-35200-16580]
  2. Bioactive Food Components for Optimal Health Program [31.0]
  3. National Institutes of Health [HD057493, DC04702]

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Objectives: To evaluate whether serum RBP4 correlates with gestational diabetes mellitus (GDM) in a cohort of borderline obese (BMI > 30) pregnant women. Design and methods: Serum RBP4 and retinol were measured in pregnant women with (n = 12) and without (n = 10) GDM. Results: RBP4, retinol and RBP4:retinol molar ratio were not different between the groups and were not associated with markers of insulin resistance. Conclusions: GDM is not associated with RBP4 or retinol among borderline obese pregnant women. (C) 2009 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

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