4.3 Review

Novel therapeutic approaches in multiple system atrophy

Related references

Note: Only part of the references are listed.
Article Clinical Neurology

Cerebellar and parkinsonian phenotypes in multiple system atrophy: similarities, differences and survival

Dusan Roncevic et al.

JOURNAL OF NEURAL TRANSMISSION (2014)

Review Clinical Neurology

Extracellular α-synuclein-a novel and crucial factor in Lewy body diseases

He-Jin Lee et al.

NATURE REVIEWS NEUROLOGY (2014)

Article Biochemistry & Molecular Biology

Modulation of α-synuclein fibrillization by ring-fused 2-pyridones: Templation and inhibition involve oligomers with different structure

Istvan Horvath et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2013)

Article Biochemistry & Molecular Biology

Oxidation and nitration of α-synuclein and their implications in neurodegenerative diseases

Cecilia Chavarria et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2013)

Article Clinical Neurology

Prion-like spreading of pathological α-synuclein in brain

Masami Masuda-Suzukake et al.

BRAIN (2013)

Article Clinical Neurology

A randomized clinical trial of lithium in multiple system atrophy

Francesco Sacca et al.

JOURNAL OF NEUROLOGY (2013)

Article Clinical Neurology

The natural history of multiple system atrophy: a prospective European cohort study

Gregor K. Wenning et al.

LANCET NEUROLOGY (2013)

Letter Multidisciplinary Sciences

Properties of native brain α-synuclein

Jacqueline Burre et al.

NATURE (2013)

Article Multidisciplinary Sciences

Transmission of multiple system atrophy prions to transgenic mice

Joel C. Watts et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Clinical Neurology

A Randomized Trial of Mesenchymal Stem Cells in Multiple System Atrophy

Phil Hyu Lee et al.

ANNALS OF NEUROLOGY (2012)

Article Biochemistry & Molecular Biology

Binding of neuronal α-synuclein to β-III tubulin and accumulation in a model of multiple system atrophy

Kimiko Nakayama et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)

Article Biochemistry & Molecular Biology

Differential inhibition of α-synuclein oligomeric and fibrillar assembly in parkinson's disease model by cinnamon extract

Ronit Shaltiel-Karyo et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2012)

Article Clinical Neurology

Treatment of multiple system atrophy using intravenous immunoglobulin

Peter Novak et al.

BMC NEUROLOGY (2012)

Article Neurosciences

Fluoxetine rescues impaired hippocampal neurogenesis in a transgenic A53T synuclein mouse model

Zacharias Kohl et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2012)

Article Biochemistry & Molecular Biology

Role of α-synuclein penetration into the membrane in the mechanisms of oligomer pore formation

Igor F. Tsigelny et al.

FEBS JOURNAL (2012)

Letter Clinical Neurology

Maintaining glottic opening in multiple system atrophy: Efficacy of serotonergic therapy

Tetsutaro Ozawa et al.

MOVEMENT DISORDERS (2012)

Article Multidisciplinary Sciences

Oligodendroglia metabolically support axons and contribute to neurodegeneration

Youngjin Lee et al.

NATURE (2012)

Article Medicine, Research & Experimental

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

Christian Hansen et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Article Clinical Neurology

Fluoxetine protects neurons against microglial activation-mediated neurotoxicity

Feng Zhang et al.

PARKINSONISM & RELATED DISORDERS (2011)

Article Immunology

Specific antibodies to soluble alpha-synuclein conformations in intravenous immunoglobulin preparations

L. M. Patrias et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2010)

Review Biochemistry & Molecular Biology

Riluzole, Neuroprotection and Amyotrophic Lateral Sclerosis

B. C. Cheah et al.

CURRENT MEDICINAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies

He-Jin Lee et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Review Physiology

Glutamate receptors, neurotoxicity and neurodegeneration

Anthony Lau et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2010)

Article Biochemistry & Molecular Biology

β-Sheet-breaking peptides inhibit the fibrillation of human α-synuclein

You Soon Kim et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)

Review Neurosciences

GLUTAMATERGIC SIGNALING IN THE BRAIN'S WHITE MATTER

Y. Bakiri et al.

NEUROSCIENCE (2009)

Article Medicine, General & Internal

A Double-Blind, Delayed-Start Trial of Rasagiline in Parkinson's Disease

C. Warren Olanow et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Multidisciplinary Sciences

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein

Paula Desplats et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Neurosciences

Rasagiline is neuroprotective in a transgenic model of multiple system atrophy

Nadia Stefanova et al.

EXPERIMENTAL NEUROLOGY (2008)

Article Biochemistry & Molecular Biology

Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein

He-Jin Lee et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)

Article Clinical Neurology

The efficacy of combined estrogen and buspirone treatment in olivopontocerebellar atrophy

Jae-Hyeok Heo et al.

JOURNAL OF THE NEUROLOGICAL SCIENCES (2008)

Article Neurosciences

P2X7 Receptors in Oligodendrocytes: A Novel Target for Neuroprotection

Carlos Matute

MOLECULAR NEUROBIOLOGY (2008)

Article Biochemistry & Molecular Biology

Origins and effects of extracellular alpha-synuclein: Implications in Parkinson's disease

Seung-Jae Lee

JOURNAL OF MOLECULAR NEUROSCIENCE (2008)

Review Pharmacology & Pharmacy

White matter NMDA receptors: an unexpected new therapeutic target?

Peter K. Stys et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2007)

Article Clinical Neurology

Multiple system atrophy:: α-synuclein and neuronal degeneration

Mari Yoshida

NEUROPATHOLOGY (2007)

Article Biochemistry & Molecular Biology

Minocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC)α/βII

Maria Nikodemova et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Biochemistry & Molecular Biology

Microglial activation and its implications in the brain diseases

S. Thameem Dheen et al.

CURRENT MEDICINAL CHEMISTRY (2007)

Article Clinical Neurology

Cellular pathology in multiple system atrophy

Koichi Wakabayashi et al.

NEUROPATHOLOGY (2006)

Article Biochemistry & Molecular Biology

Mesenchymal stem cells as trophic mediators

Arnold I. Caplan et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2006)

Article Neurosciences

Activation of kainate receptors sensitizes oligodendrocytes to complement attack

E Alberdi et al.

JOURNAL OF NEUROSCIENCE (2006)

Article Clinical Neurology

Paroxetine treatment improves motor symptoms in patients with multiple system atrophy

Elisabeth Friess et al.

PARKINSONISM & RELATED DISORDERS (2006)

Article Clinical Neurology

Absence of α-synuclein mRNA expression in normal and multiple system atrophy oligodendroglia

DW Miller et al.

JOURNAL OF NEURAL TRANSMISSION (2005)

Article Multidisciplinary Sciences

Peroxynitrite generated by inducible nitric oxide synthase and NADPH oxidase mediates microglial toxicity to oligodendrocytes

JR Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

P25α stimulates a-synuclein aggregation and is co-localized with aggregated α-synuclein in α-synucleinopathies

E Lindersson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Clinical Neurology

Microglial activation parallels system degeneration in multiple system atrophy

K Ishizawa et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)

Article Medicine, Research & Experimental

Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation

M Dezawa et al.

JOURNAL OF CLINICAL INVESTIGATION (2004)