3.9 Article

Antibodies Induced by Dengue Virus Type 1 and 2 Envelope Domain III Recombinant Proteins in Monkeys Neutralize Strains with Different Genotypes

Journal

CLINICAL AND VACCINE IMMUNOLOGY
Volume 16, Issue 12, Pages 1829-1831

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/CVI.00191-09

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Funding

  1. Cuban Program for Dengue Vaccine Development

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In the present work, we evaluated the neutralizing capacity of the antibodies induced by dengue virus type 1 and 2 envelope domain III recombinant proteins in monkeys against strains of different dengue virus type 1 and 2 genotypes. Here we demonstrated that dengue virus type 1 and 2 recombinant proteins induced high titers of neutralizing antibodies against different genotype strains.

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