Journal
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
Volume 40, Issue 4, Pages 358-363Publisher
WILEY
DOI: 10.1111/j.1442-9071.2011.02744.x
Keywords
endophenotype; genetics; primary open-angle glaucoma; quantitative trait loci
Categories
Funding
- National Health and Medical Research Council
Ask authors/readers for more resources
Genome-wide association studies are a powerful tool for the identification of genetic risk factors for complex disease. This methodology has been successfully applied to primary open-angle glaucoma through the analysis of primary open-angle glaucoma (POAG) as well as specific subgroups of patients including those with normal tension glaucoma and advanced glaucoma. In addition, the analysis of quantitative traits important in POAG, including optic disc area and vertical cup-to-disc ratio has also identified genes important in POAG development. This review explores findings of genome-wide association studies for POAG and related traits.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available