Journal
CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Volume 155, Issue 1, Pages 1-15Publisher
WILEY
DOI: 10.1111/j.1365-2249.2008.03834.x
Keywords
autoimmune disease; molecular mimicry; virus infection
Categories
Funding
- NINDS NIH HHS [P01 NS023349] Funding Source: Medline
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [P01NS023349] Funding Source: NIH RePORTER
Ask authors/readers for more resources
Autoimmunity occurs when the immune system recognizes and attacks host tissue. In addition to genetic factors, environmental triggers (in particular viruses, bacteria and other infectious pathogens) are thought to play a major role in the development of autoimmune diseases. In this review, we (i) describe the ways in which an infectious agent can initiate or exacerbate autoimmunity; (ii) discuss the evidence linking certain infectious agents to autoimmune diseases in humans; and (iii) describe the animal models used to study the link between infection and autoimmunity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available