Journal
CLINICAL AND EXPERIMENTAL HYPERTENSION
Volume 36, Issue 4, Pages 211-216Publisher
INFORMA HEALTHCARE
DOI: 10.3109/10641963.2013.804546
Keywords
Chronic kidney disease; hypertension; inflammation; sleep apnea
Funding
- University of Medicine and Pharmacy Iasi [1640/01.02.2013]
- IDEI - PCE [PN-II-ID-PCE-2011-3-0637]
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Clinical and experimental studies revealed that sleep apnea might be an insidious risk factor for the progression of kidney disease and development of cardiovascular events by exacerbating well-known risk factors, namely hypertension, type 2 diabetes mellitus and obesity. Furthermore, sleep apnea also has a negative impact on endothelial function. Therefore, sleep apnea might be defined as a new cardiorenal risk factor. In this review, we aimed to summarize the evidences supporting the complex inter-relations between sleep apnea and development and progression of chronic kidney disease.
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