Journal
CLINICAL ANATOMY
Volume 27, Issue 2, Pages 201-209Publisher
WILEY
DOI: 10.1002/ca.22280
Keywords
yawning; arousal; sleep; adenosine; default mode network; cerebrospinal fluid
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Yawning is a behavior to which little research has been devoted. However, its purpose has not yet been demonstrated and remains controversial. In this article, we propose a new theory involving the brain network that is functional during the resting state, that is, the default mode network. When this network is active, yawning manifests a process of switching to the attentional system through its capacity to increase circulation of cerebrospinal fluid (CSF), thereby increasing clearance of somnogenic factors (prostaglandin D(2), adenosine, and others) accumulating in the cerebrospinal fluid. Clin. Anat. 27:201-209, 2014. (c) 2013 Wiley Periodicals, Inc.
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