Journal
CLINICAL & TRANSLATIONAL ONCOLOGY
Volume 11, Issue 5, Pages 329-331Publisher
SPRINGER INTERNATIONAL PUBLISHING AG
DOI: 10.1007/s12094-009-0363-5
Keywords
Ovarian cancer; Bevacizumab; Cyclophosphamide; Low-dose metronomic chemotherapy
Categories
Ask authors/readers for more resources
During the last decade we have been developing new therapeutic strategies for the treatment of ovarian cancer, based on the best knowledge of the molecular biology. New drugs like bevacizumab are showing antiangiogenic antitumour activity in ovarian cancer in preclinical models and in clinical trials. Bevacizumab is a monoclonal human antibody that has showed activity in both monotherapy and in combination with other therapies. We present the outcome of two patient cases with recurring heavily pre-treated ovarian cancer that were treated with cyclophosphamide and bevacizumab in combination and showed a complete remission of disease. After interruption of the treatment with bevacizumab, both patients had a disease relapse. Despite poor prognosis of the disease, in both cases a second complete and maintained remission was achieved, again with the same regimen.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available