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T Cells in Gastric Cancer: Friends or Foes

Journal

CLINICAL & DEVELOPMENTAL IMMUNOLOGY
Volume -, Issue -, Pages -

Publisher

HINDAWI LTD
DOI: 10.1155/2012/690571

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Funding

  1. Ministry of University and Research
  2. Italian Ministry of Health

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Gastric cancer is the second cause of cancer-related deaths worldwide. Helicobacter pylori is the major risk factor for gastric cancer. As for any type of cancer, T cells are crucial for recognition and elimination of gastric tumor cells. Unfortunately T cells, instead of protecting from the onset of cancer, can contribute to oncogenesis. Herein we review the different types, friend or foe, of T-cell response in gastric cancer.

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