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Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire
Matthew A. Burchill et al.
IMMUNITY (2008)
A two-step process for thymic regulatory T cell development
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IMMUNITY (2008)
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma
Xuexian O. Yang et al.
IMMUNITY (2008)
Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
Xuexian O. Yang et al.
IMMUNITY (2008)
TAB4 stimulates TAK1-TAB1 phosphorylation and binds polyubiquitin to direct signaling to NF-κB
Todd D. Prickett et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans
Elin Jaensson et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
PI3K is critical for the nuclear translocation of IRF-7 and type IIFN production by human plasmacytoid predendritic cells in response to TLR activation
Cristiana Guiducci et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Dissecting T cell lineage relationships by cellular barcoding
Koen Schepers et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Reversible Blockade of Thymic Output: An Inherent Part of TLR Ligand-Mediated Immune Response
Thomas Demoulins et al.
JOURNAL OF IMMUNOLOGY (2008)
TLR ligand-induced type IIFNs affect thymopoiesis
Marie-Laurence Baron et al.
JOURNAL OF IMMUNOLOGY (2008)
Nasal Anti-CD3 Antibody Ameliorates Lupus by Inducing an IL-10-Secreting CD4+CD25-LAP+ Regulatory T Cell and Is Associated with Down-Regulation of IL-17+CD4+ICOS+CXCR5+ Follicular Helper T Cells
Henry Yim Wu et al.
JOURNAL OF IMMUNOLOGY (2008)
Thymic emigration: When and how T cells leave home
Michael A. Weinreich et al.
JOURNAL OF IMMUNOLOGY (2008)
Live Lactobacillus rhamnosus and Streptococcus pyogenes differentially regulate Toll-like receptor (TLR) gene expression in human primary macrophages
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UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
You-Me Kim et al.
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The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor
Sarah E. Ewald et al.
NATURE (2008)
Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
Marc Veldhoen et al.
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IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3- effector T cells
Valerie Dardalhon et al.
NATURE IMMUNOLOGY (2008)
Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2
Tatsukata Kawagoe et al.
NATURE IMMUNOLOGY (2008)
Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9
Boyoun Park et al.
NATURE IMMUNOLOGY (2008)
Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules
ZhiChao Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation
Nicholas van Panhuys et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Dendritic cells in the thymus contribute to T-regulatory cell induction
Anna I. Proietto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Deletional tolerance mediated by extrathymic Aire-expressing cells
James M. Gardner et al.
SCIENCE (2008)
Functional differences between M cells and enterocytes in sampling luminal antigens
Jennelle M. Kyd et al.
VACCINE (2008)
Dendritic cells in intestinal immune regulation
Janine L. Coombes et al.
NATURE REVIEWS IMMUNOLOGY (2008)
A single naive CD8+ T cell precursor can develop into diverse effector and memory subsets
Christian Stemberger et al.
IMMUNITY (2007)
A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells
Amit Awasthi et al.
NATURE IMMUNOLOGY (2007)
Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature
Jonathan A. Hill et al.
IMMUNITY (2007)
Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection
Scott N. Mueller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells
Andrew M. Intlekofer et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
Liang Zhou et al.
NATURE IMMUNOLOGY (2007)
Loss of T cell receptor-induced Bmi-1 in the KLRG1+ senescent CD8+ T lymphocyte
Maike Heffner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
MyD88-mediated signals induce the bactericidal lectin RegIIIγ and protect mice against intestinal Listeria monocytogenes infection
Katharina Brandl et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β- and retinoic acid-dependent mechanism
Janine L. Coombes et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Noninvasive intravital imaging of thymocyte dynamics in medaka
Jie Li et al.
JOURNAL OF IMMUNOLOGY (2007)
Inflammation directs memory precursor and short-lived effector CD8+ T cell fates via the graded expression of T-bet transcription factor
Nikhil S. Joshi et al.
IMMUNITY (2007)
IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
Thomas Korn et al.
NATURE (2007)
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
Roza Nurieva et al.
NATURE (2007)
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
Daniel Mucida et al.
SCIENCE (2007)
TLR signaling mediated by MyD88 is required for a protective innate immune response by Neutrophils to Citrobacter rodentium
Sarah L. Lebeis et al.
JOURNAL OF IMMUNOLOGY (2007)
The perivascular space as a path of hematopoietic progenitor cells and mature T cells between the blood circulation and the thymic parenchyma
Kazuya Mori et al.
INTERNATIONAL IMMUNOLOGY (2007)
Nonredundant roles for Stat5a/b in directly regulating Foxp3
Zhengju Yao et al.
BLOOD (2007)
Gnotobiotic IL-10-/-;NF-κBEGFP mice reveal the critical role of TLR/NF-κB signaling in commensal bacteria-induced colitis
Thomas Karrasch et al.
JOURNAL OF IMMUNOLOGY (2007)
NKG2D recognition mediates Toll-like receptor 3 signaling-induced breakdown of epithelial homeostasis in the small intestines of mice
Rongbin Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling
Melanie M. Brinkmann et al.
JOURNAL OF CELL BIOLOGY (2007)
Regulatory T cell development in the absence of functional Foxp3
Wen Lin et al.
NATURE IMMUNOLOGY (2007)
Cutting edge:: IL-2 is essential for TGF-β-mediated induction of Foxp3+ T regulatory cells
Todd S. Davidson et al.
JOURNAL OF IMMUNOLOGY (2007)
STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
Xuexian O. Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Asymmetric T lymphocyte division in the initiation of adaptive immune responses
John T. Chang et al.
SCIENCE (2007)
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
Luke M. Williams et al.
NATURE IMMUNOLOGY (2007)
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
Yisong Y. Wan et al.
NATURE (2007)
CpG DNA inhibits CD4+CD25+ Treg suppression through direct MyD88-dependent costimulation of effector CD4+ T cells
David F. LaRosa et al.
IMMUNOLOGY LETTERS (2007)
Foxp3-dependent programme of regulatory T-cell differentiation
Marc A. Gavin et al.
NATURE (2007)
Two tyrosine residues of Toll-like receptor 3 trigger different steps of NF-κB activation
Saumendra N. Sarkar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Suppression of early IL-4 production underlies the failure of CD4 T cells activated by TLR-stimulated dendritic cells to differentiate into Th2 cells
Jie Sun et al.
JOURNAL OF IMMUNOLOGY (2007)
Translational mini-review series on Toll-like receptors: Networks regulated by Toll-like receptors mediate innate and adaptive immunity
L. C. Parker et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2007)
Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self
Je-Wook Lee et al.
NATURE IMMUNOLOGY (2007)
Expression and function of Toll-like receptors in T lymphocytes
Dieter Kabelitz
CURRENT OPINION IN IMMUNOLOGY (2007)
IL-2 receptor β-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells
Matthew A. Burchill et al.
JOURNAL OF IMMUNOLOGY (2007)
Immunobiology of Toll-like receptors in allergic disease
Stefan Bauer et al.
IMMUNOBIOLOGY (2007)
Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement
Marcello Chieppa et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells
Jongdae Lee et al.
NATURE CELL BIOLOGY (2006)
Cytoplasmic targeting motifs control localization of toll-like receptor 9
Cynthia A. Leifer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells
J. Rodrigo Mora et al.
SCIENCE (2006)
Lipopolysaccharide-activated CD4+CD25+ T regulatory cells inhibit neutrophil function and promote their apoptosis and death
Przemyslaw Lewkowicz et al.
JOURNAL OF IMMUNOLOGY (2006)
Induction of tolerance to innocuous inhaled antigen relies on a CCR7-dependent dendritic cell-mediated antigen transport to the bronchial lymph node
Gabriele Hintzen et al.
JOURNAL OF IMMUNOLOGY (2006)
The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation
Andrew E. Gelman et al.
IMMUNITY (2006)
Coordination between CCR7-and CCR9-mediated chemokine signals in prevascular fetal thymus colonization
Cunlan Liu et al.
BLOOD (2006)
Confronting complexity:: Real-world immunodominance in antiviral CD8+ T cell responses
Jonathan W. Yewdell
IMMUNITY (2006)
Clonal deletion of thymocytes by circulating dendritic cells homing to the thymus
Roberto Bonasio et al.
NATURE IMMUNOLOGY (2006)
The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells
Ivaylo I. Ivanov et al.
CELL (2006)
TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis
Carolyn G. King et al.
NATURE MEDICINE (2006)
Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria
Masaru Yoshida et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Toll-like receptors on regulatory T cells: expanding immune regulation
Roger P. M. Sutmuller et al.
TRENDS IN IMMUNOLOGY (2006)
Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling
Ingvild Bjellmo Johnsen et al.
EMBO JOURNAL (2006)
被撤回的出版物: Heat shock protein 60 enhances CD4+CD25+ regulatory T cell function via innate TLR2 signaling (Retracted article. See vol. 128, pg. 2651, 2018)
Alexandra Zanin-Zhorov et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
TLR2 engagement on CD8 T cells lowers the threshold for optimal antigen-induced T cell activation
Anne Cottalorda et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
Plasmacytoid dendritic cell-specific receptor ILT7-FcεRIγ inhibits Toll-like receptor-induced interferon production
Wei Cao et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+ CD25-LAP+ T cells
Hirofumi Ochi et al.
NATURE MEDICINE (2006)
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
E Bettelli et al.
NATURE (2006)
Toll-like receptor 2 signaling modulates the functions of CD4+CD25+ regulatory T cells
HY Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Regulation of intestinal dendritic cell migration and activation by plasmacytoid dendritic cells, TNF-α and type 1 IFNs after feeding a TLR7/8 ligand
Ulf Yrlid et al.
JOURNAL OF IMMUNOLOGY (2006)
Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells
M Lotz et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction
P Gray et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Toll-dependent selection of microbial antigens for presentation by dendritic cells
JM Blander et al.
NATURE (2006)
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9
K Tabeta et al.
NATURE IMMUNOLOGY (2006)
Toll-like receptor 2 controls expansion and function of regulatory T cells
RPM Sutmuller et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
H Häcker et al.
NATURE (2006)
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
G Oganesyan et al.
NATURE (2006)
Oral tolerance: Therapeutic implications for autoimmune diseases
Ana M. C. Faria et al.
CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2006)
Essay - Dendritic cells in a mature age
Caetano Reis e Sousa
NATURE REVIEWS IMMUNOLOGY (2006)
Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells
NK Crellin et al.
JOURNAL OF IMMUNOLOGY (2005)
Host-reactive CD8+ memory stem cells in graft-versus-host disease
Y Zhang et al.
NATURE MEDICINE (2005)
Control of B-cell responses by Toll-like receptors
C Pasare et al.
NATURE (2005)
Rip1 mediates the Trif-dependent Toll-like receptor 3- and 4-induced NF-κB activation but does not contribute to interferon regulatory factor 3 activation
N Cusson-Hermance et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements
T Nishiya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Negative regulation of Toll-like-receptor signaling by IRF-4
H Negishi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Toll-like, receptor 8-mediated reversal of CD4+ regulatory T cell function
GY Peng et al.
SCIENCE (2005)
Oral tolerance in the absence of naturally occurring Tregs
D Mucida et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Recruitment of adult thymic progenitors is regulated by P-selectin and its ligand PSGL-1
FMV Rossi et al.
NATURE IMMUNOLOGY (2005)
Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction
K Honda et al.
NATURE (2005)
Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif
WJ Kaiser et al.
JOURNAL OF IMMUNOLOGY (2005)
IRF-7 is the master regulator of type-I interferon-dependent immune responses
K Honda et al.
NATURE (2005)
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
A Takaoka et al.
NATURE (2005)
Cutting edge:: TLR ligands are not sufficient to break cross-tolerance to self-antigens
EE Hamilton-Williams et al.
JOURNAL OF IMMUNOLOGY (2005)
Cutting edge: NF-kappa B-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation
M Sasai et al.
JOURNAL OF IMMUNOLOGY (2005)
Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration
ML Allende et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Human thymic stromal lymphopoietin promotes dendritic cell-mediated CD4+ T cell homeostatic expansion
N Watanabe et al.
NATURE IMMUNOLOGY (2004)
Mechanisms of cross hyporesponsiveness to toll-like receptor bacterial ligands in intestinal epithelial cells
JM Otte et al.
GASTROENTEROLOGY (2004)
TLR2 is expressed on activated T cells as a costimulatory receptor
M Komai-Koma et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Identification of a human NF-κB-activating protein, TAB3
G Jin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells
SY Pai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
M Matloubian et al.
NATURE (2004)
Retinoic acid imprints gut-homing specificity on T cells
M Iwata et al.
IMMUNITY (2004)
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
S Rakoff-Nahoum et al.
CELL (2004)
Direct Toll-like receptor 2 mediated co-stimulation of T cells in the mouse system as a basis for chronic inflammatory joint disease
V Sobek et al.
ARTHRITIS RESEARCH & THERAPY (2004)
T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells
T Chtanova et al.
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Conditional deletion of Gata3 shows its essential function in TH1-TH2 responses
JF Zhu et al.
NATURE IMMUNOLOGY (2004)
Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling
SN Sarkar et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Therapeutic potential of oral tolerance
L Mayer et al.
NATURE REVIEWS IMMUNOLOGY (2004)
Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation
AM Gallegos et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Toll-like receptor ligands directly promote activated CD4+ T cell survival
AE Gelman et al.
JOURNAL OF IMMUNOLOGY (2004)
Control of effector CD8+ T cell function by the transcription factor Eomesodermin
EL Pearce et al.
SCIENCE (2003)
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
JD Fontenot et al.
NATURE IMMUNOLOGY (2003)
Toll-like receptor expression in murine DC subsets:: lack of TLR7 expression by CD8α+ DC correlates with unresponsiveness to imidazoquinolines
AD Edwards et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2003)
Stimulation by food proteins plays a critical role in the maturation of the immune system
JD Menezes et al.
INTERNATIONAL IMMUNOLOGY (2003)
Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide
I Caramalho et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Control of regulatory T cell development by the transcription factor Foxp3
S Hori et al.
SCIENCE (2003)
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
C Pasare et al.
SCIENCE (2003)
TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-β induction
H Oshiumi et al.
NATURE IMMUNOLOGY (2003)
Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: Dependency on antigen dose and differential toll-like receptor ligation
A Boonstra et al.
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TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway
M Yamamoto et al.
NATURE IMMUNOLOGY (2003)
Stat5 activation plays a critical role in Th2 differentiation
JF Zhu et al.
IMMUNITY (2003)
Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen
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JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Cutting edge:: A novel toll/IL-1 receptor Domain containing adapter that preferentially activates the IFN-β promoter in the toll-like receptor signaling
M Yamamoto et al.
JOURNAL OF IMMUNOLOGY (2002)
Projection of an immunological self shadow within the thymus by the aire protein
MS Anderson et al.
SCIENCE (2002)
Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus
M Yamashita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Activation of APCs through CD40 or toll-like receptor 9 overcomes tolerance and precipitates autoimmune disease
HT Ichikawa et al.
JOURNAL OF IMMUNOLOGY (2002)
Variable expression of Toll-like receptor in murine innate and adaptive immune cell lines
SE Applequist et al.
INTERNATIONAL IMMUNOLOGY (2002)
Hlx is induced by and genetically interacts with T-bet to promote heritable TH1 gene induction
AC Mullen et al.
NATURE IMMUNOLOGY (2002)
T-bet is a STAT1-induced regulator of IL-12R expression in naive CD4+ T cells
M Afkarian et al.
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Quantitative expression of Toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
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Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
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Decoding the patterns of self and nonself by the innate immune system
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Tissue expression of human toll-like receptors and differential regulation of toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
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JOURNAL OF IMMUNOLOGY (2002)
Distinct effects of T-bet in TH1 lineage commitment and IFN-γ production in CD4 and CD8 T cells
SJ Szabo et al.
SCIENCE (2002)
T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells
AA Lighvani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Thymus medulla consisting of epithelial islets each derived from a single progenitor
HR Rodewald et al.
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Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
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NATURE IMMUNOLOGY (2001)
Toll-like receptors control activation of adaptive immune responses
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NATURE IMMUNOLOGY (2001)
Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
N Kadowaki et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
KA Fitzgerald et al.
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TIRAP: an adapter molecule in the Toll signaling pathway
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NATURE IMMUNOLOGY (2001)
Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen
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NATURE IMMUNOLOGY (2001)
Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development
EF Lind et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Stat6 is necessary and sufficient for IL-4's role in Th2 differentiation and cell expansion
JF Zhu et al.
JOURNAL OF IMMUNOLOGY (2001)
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection
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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
CL Bennett et al.
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Down-regulation of p27(Kip1) expression is required for development and function of T cells
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Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells
M Muzio et al.
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Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo
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A novel transcription factor, T-bet, directs Th1 lineage commitment
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CELL (2000)
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