Journal
CLEVELAND CLINIC JOURNAL OF MEDICINE
Volume 80, Issue 4, Pages 225-233Publisher
CLEVELAND CLINIC
DOI: 10.3949/ccjm.80a.12182
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Funding
- National Center for Advancing Translational Sciences (NCATS) component of the National Institutes of Health [UL1TR000439]
- NIH roadmap for Medical Research
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The emergence of carbapenem-resistant Enterobacteriaceae (CRE) highlights the importance of effective antibiotics to maintain the safety of our health care system. Clinicians will encounter CRE as a cause of difficult-to-treat and often fatal infections in hospitalized patients. We review the mechanisms of carbapenem resistance, the dissemination and clinical impact of these resistant organisms, and challenges to their detection, treatment, and control.
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