4.8 Article

High-Fidelity Noncovalent Synthesis of Hydrogen-Bonded Macrocyclic Assemblies

Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 54, Issue 23, Pages 6780-6784

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201501321

Keywords

chelates; noncovalent interactions; nucleosides; self-assembly; supramolecular chemistry

Funding

  1. MINECO [CTQ2011-23659]
  2. E.U. (ERC) [279548]
  3. European Research Council (ERC) [279548] Funding Source: European Research Council (ERC)

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A hydrogen-bonded cyclic tetramer is assembled with remarkably high effective molarities from a properly designed dinucleoside monomer. This self-assembled species exhibits an impressive thermodynamic and kinetic stability and is formed with high fidelities within a broad concentration range.

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