4.7 Review

Physiological Roles of the Permeability Transition Pore

Related references

Note: Only part of the references are listed.
Article Cardiac & Cardiovascular Systems

Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo

Martinus I. F. J. Oerlemans et al.

BASIC RESEARCH IN CARDIOLOGY (2012)

Review Biochemistry & Molecular Biology

SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging

Albert Giralt et al.

BIOCHEMICAL JOURNAL (2012)

Review Biochemistry & Molecular Biology

Voltage-dependant anion channels: Novel insights into isoform function through genetic models

Adithya Raghavan et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)

Review Cardiac & Cardiovascular Systems

The mPTP and its regulatory proteins: final common targets of signalling pathways for protection against necrosis

Tetsuji Miura et al.

CARDIOVASCULAR RESEARCH (2012)

Article Cardiac & Cardiovascular Systems

Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload

Jerome Piquereau et al.

CARDIOVASCULAR RESEARCH (2012)

Article Biochemistry & Molecular Biology

p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis

Angelina V. Vaseva et al.

Review Biochemistry & Molecular Biology

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

L. Galluzzi et al.

CELL DEATH AND DIFFERENTIATION (2012)

Article Medicine, Research & Experimental

Hexokinase II knockdown results in exaggerated cardiac hypertrophy via increased ROS production

Rongxue Wu et al.

EMBO MOLECULAR MEDICINE (2012)

Article Pharmacology & Pharmacy

Pharmaceutical development of the novel arsenical based cancer therapeutic GSAO for Phase I clinical trial

M. A. Elliott et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2012)

Review Multidisciplinary Sciences

Mitochondrial Fission, Fusion, and Stress

Richard J. Youle et al.

SCIENCE (2012)

Review Endocrinology & Metabolism

Protein carbonylation and metabolic control systems

Jessica M. Curtis et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2012)

Review Biochemical Research Methods

Inhibition of the Mitochondrial Permeability Transition for Cytoprotection: Direct versus Indirect Mechanisms

Cecile Martel et al.

BIOCHEMISTRY RESEARCH INTERNATIONAL (2012)

Article Cell Biology

Sirt3 Targets mPTP and Prevents Aging in the Heart

Junichi Sadoshima

AGING-US (2011)

Review Cardiac & Cardiovascular Systems

Emerging characterization of the role of SIRT3-mediated mitochondrial protein deacetylation in the heart

Michael N. Sack

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)

Article Cardiac & Cardiovascular Systems

Disruption of Hexokinase II-Mitochondrial Binding Blocks Ischemic Preconditioning and Causes Rapid Cardiac Necrosis

Kirsten M. A. Smeele et al.

CIRCULATION RESEARCH (2011)

Article Biochemistry & Molecular Biology

Cysteine 203 of Cyclophilin D Is Critical for Cyclophilin D Activation of the Mitochondrial Permeability Transition Pore

Tiffany T. Nguyen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Review Cell Biology

Mitochondrial Unselective Channels throughout the eukaryotic domain

Salvador Uribe-Carvajal et al.

MITOCHONDRION (2011)

Review Biochemistry & Molecular Biology

Adenine nucleotide translocase family: four isoforms for apoptosis modulation in cancer

C. Brenner et al.

ONCOGENE (2011)

Article Cell Biology

Necroptosis as an alternative form of programmed cell death

Dana E. Christofferson et al.

CURRENT OPINION IN CELL BIOLOGY (2010)

Review Biochemistry & Molecular Biology

Electrophysiology clarifies the megariddles of the mitochondrial permeability transition pore

Mario Zoratti et al.

FEBS LETTERS (2010)

Review Biochemistry & Molecular Biology

Signal transduction to the permeability transition pore

Andrea Rasola et al.

FEBS LETTERS (2010)

Article Biochemistry & Molecular Biology

The fourth isoform of the adenine nucleotide translocator inhibits mitochondrial apoptosis in cancer cells

Cindy Gallerne et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Glutathionylation of Adenine Nucleotide Translocase Induced by Carbon Monoxide Prevents Mitochondrial Membrane Permeabilization and Apoptosis

Claudia S. F. Queiroga et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Medicine, Research & Experimental

Cyclophilin D controls mitochondrial pore-dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice

John W. Elrod et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Pharmacology & Pharmacy

TRO40303, a New Cardioprotective Compound, Inhibits Mitochondrial Permeability Transition

Sophie Schaller et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)

Review Cell Biology

Molecular mechanisms of necroptosis: an ordered cellular explosion

Peter Vandenabeele et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Adenine nucleotide translocator 1 deficiency increases resistance of mouse brain and neurons to excitotoxic insults

Jaewon Lee et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2009)

Article Biochemistry & Molecular Biology

Differential CpG island methylation of murine adenine nucleotide translocase genes

Jeffrey V. Brower et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2009)

Review Biochemistry & Molecular Biology

Adenine nucleotide translocase: a component of the phylogenetically conserved cell death machinery

B. Zhivotovsky et al.

CELL DEATH AND DIFFERENTIATION (2009)

Review Biochemistry & Molecular Biology

Inhibition of Mitochondrial Membrane Permeability as a Putative Pharmacological Target for Cardioprotection

D. Morin et al.

CURRENT MEDICINAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Pharmacological screening and enzymatic assays for apoptosis

Anne-Sophie Belzacq-Casagrande et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2009)

Article Biochemistry & Molecular Biology

Mitoparan and target-selective chimeric analogues: Membrane translocation and intracellular redistribution induces mitochondrial apoptosis

Sarah Jones et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)

Article Biochemistry & Molecular Biology

The mitochondrial phosphate carrier interacts with cyclophilin D and may play a key role in the permeability transition

Anna W. C. Leung et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70

Nagalingam R. Sundaresan et al.

MOLECULAR AND CELLULAR BIOLOGY (2008)

Article Medicine, General & Internal

Effect of cyclosporine on reperfusion injury in acute myocardial infarction

Christophe Piot et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Article Biochemistry & Molecular Biology

ADP/ATP carrier is required for mitochondrial permeabilization and cytochrome c release in yeast apoptosis

Clara Pereira et al.

MOLECULAR MICROBIOLOGY (2007)

Article Biochemistry & Molecular Biology

Evolutionarily conserved mammalian adenine nucleotide translocase 4 is essential for spermatogenesis

Jeffrey V. Brower et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Pharmacology & Pharmacy

Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis

Thierry Bordet et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)

Article Biochemistry & Molecular Biology

Role of Bcl-2 family members on apoptosis: what we have learned from knock-out mice

Ramon Roset et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2007)

Article Cell Biology

Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death

Christopher P. Baines et al.

NATURE CELL BIOLOGY (2007)

Review Physiology

Mitochondrial membrane permeabilization in cell death

Guido Kroemer et al.

PHYSIOLOGICAL REVIEWS (2007)

Article Biochemistry & Molecular Biology

Electrophysiological characterization of the Cyclophilin D-deleted mitochondrial permeability transition pore

Umberto De Marchi et al.

MOLECULAR MEMBRANE BIOLOGY (2006)

Review Biochemistry & Molecular Biology

The permeability transition pore complex in cancer cell death

C. Brenner et al.

ONCOGENE (2006)

Article Multidisciplinary Sciences

Tim50 maintains the permeability barrier of the mitochondrial inner membrane

Michael Meinecke et al.

SCIENCE (2006)

Article Biochemistry & Molecular Biology

Properties of the permeability transition in VDAC1-/- mitochondria

Alexandra Krauskopf et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2006)

Article Cardiac & Cardiovascular Systems

Exercise training induces respiratory substrate-specific decrease in Ca2+-induced permeability transition pore opening in heart mitochondria

M Marcil et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)

Article Biochemistry & Molecular Biology

Properties of the permeability transition pore in mitochondria devoid of cyclophilin D

E Basso et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Cardiac & Cardiovascular Systems

Mitochondrial function and myocardial aging. A critical analysis of the role of permeability transition

F Di Lisa et al.

CARDIOVASCULAR RESEARCH (2005)

Review Andrology

The impact of mitochondrial genetics on male infertility

JC St John et al.

INTERNATIONAL JOURNAL OF ANDROLOGY (2005)

Review Pharmacology & Pharmacy

Small interfering RNAs and antisense oligonucleotides for treatment of neurological diseases

A Forte et al.

CURRENT DRUG TARGETS (2005)

Article Biochemistry & Molecular Biology

Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells

M Zamora et al.

FEBS LETTERS (2004)

Review Cardiac & Cardiovascular Systems

Mitochondrial permeability transition pore opening during myocardial reperfusion - a target for cardioprotection

AP Halestrap et al.

CARDIOVASCULAR RESEARCH (2004)

Article Biochemistry & Molecular Biology

Recruitment of NF-κB into mitochondria is involved in adenine nucleotide translocase 1 (ANT1)-induced apoptosis

M Zamora et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Bax does not directly participate in the Ca2+-induced permeability transition of isolated mitochondria

U De Marchi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Review Biochemistry & Molecular Biology

Role of mitochondrial permeability transition pores in mitochondrial autophagy

S Rodriguez-Enriquez et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)

Article Multidisciplinary Sciences

VDAC2 inhibits BAK activation and mitochondrial apoptosis

EHY Cheng et al.

SCIENCE (2003)

Article Biochemistry & Molecular Biology

The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria

S Chalmers et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Pharmacology & Pharmacy

S-15176 inhibits mitochondrial permeability transition via a mechanism independent of its antioxidant properties

A Elimadi et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2003)

Article Biochemistry & Molecular Biology

Mitochondrial permeability transition: a common pathway to necrosis and apoptosis

JS Kim et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)

Article Biochemistry & Molecular Biology

Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis

JG Pastorino et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Immotile sperm and infertility in mice lacking mitochondrial voltage-dependent anion channel type 3

MJ Sampson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemical Research Methods

Screening assays for the mitochondrial permeability transition using a fluorescence multiwell plate reader

JR Blattner et al.

ANALYTICAL BIOCHEMISTRY (2001)

Article Biochemistry & Molecular Biology

Cytochrome c release occurs via Ca2+-dependent and Ca2+-independent mechanisms that are regulated by Bax

V Gogvadze et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

Bid acts on the permeability transition pore complex to induce apoptosis

N Zamzami et al.

ONCOGENE (2000)

Article Biophysics

Modulation of the voltage-dependent anion channel (VDAC) by glutamate

D Gincel et al.

JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2000)