Journal
CIRCULATION JOURNAL
Volume 74, Issue 3, Pages 589-591Publisher
JAPANESE CIRCULATION SOC
DOI: 10.1253/circj.CJ-09-1028
Keywords
Angina pectoris; Angiogenesis; Myocardial ischemia; Shock wave
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Funding
- Japanese Ministry of Education, Culture, Sports, Science and Technology, Tokyo
- Japanese Ministry of Health, Labor and Welfare, Tokyo, Japan
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Background: Low-energy shock wave (SW) therapy has improved myocardial ischemia in both a porcine model and in patients with severe angina pectoris. Methods and Results: To further confirm the effectiveness and safety of SW therapy, 8 patients with severe angina pectoris were treated with SW therapy in a double-blind, placebo-controlled and cross-over manner. SW therapy, but not placebo, significantly improved chest pain symptoms and cardiac function without any complications or adverse effects. Conciusions: Extracorporeal cardiac SW therapy is an effective, safe and non-invasive therapeutic option for severe angina pectoris. (Circ J 2010; 74: 589-591)
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