4.8 Article

Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease

Related references

Note: Only part of the references are listed.
Article Cardiac & Cardiovascular Systems

Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase activator, BAY 60-2770, are not dependent on endogenous nitric oxide or reduced heme

Edward A. Pankey et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)

Article Cardiac & Cardiovascular Systems

Dependence of Golgi apparatus integrity on nitric oxide in vascular cells: implications in pulmonary arterial hypertension

Jason E. Lee et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)

Article Cardiac & Cardiovascular Systems

Pre-conditioning with the soluble guanylate cyclase activator Cinaciguat reduces ischaemia-reperfusion injury after cardiopulmonary bypass

Tamas Radovits et al.

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2011)

Article Cardiac & Cardiovascular Systems

Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase stimulator, BAY 41-8543, are modulated by nitric oxide

Adeleke M. Badejo et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)

Article Pharmacology & Pharmacy

BAY 41-2272 inhibits the development of chronic hypoxic pulmonary hypertension in rats

Lise Bech Thorsen et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2010)

Review Pharmacology & Pharmacy

Emerging drugs for pulmonary hypertension

Reda E. Girgis

EXPERT OPINION ON EMERGING DRUGS (2010)

Article Cardiac & Cardiovascular Systems

CINACIGUAT, A SOLUBLE GUANYLATE CYCLASE ACTIVATOR, UNLOADS THE HEART IN ACUTE DECOMPENSATED HEART FAILURE

Erland Erdmann et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)

Review Cardiac & Cardiovascular Systems

Pulmonary hypertension with left- sided heart disease

Marco Guazzi et al.

NATURE REVIEWS CARDIOLOGY (2010)

Article Pharmacology & Pharmacy

Guanylyl cyclase activator ataciguat improves vascular function and reduces platelet activation in heart failure

Andreas Schaefer et al.

PHARMACOLOGICAL RESEARCH (2010)

Article Physiology

Novel soluble guanylyl cyclase stimulator BAY 41-2272 attenuates ischemia-reperfusion-induced lung injury

Bakytbek Egemnazarov et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)

Article Hematology

Soluble Guanylate Cyclase Agonists Inhibit Expression and Procoagulant Activity of Tissue Factor

Mikhail A. Sovershaev et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)

Article Cardiac & Cardiovascular Systems

Stimulation of cGMP signalling protects coronary endothelium against reperfusion-induced intercellular gap formation

Sascha A. Kasseckert et al.

CARDIOVASCULAR RESEARCH (2009)

Article Cardiac & Cardiovascular Systems

Pharmacological Activation of Soluble Guanylate Cyclase Protects the Heart Against Ischemic Injury

Sevil Korkmaz et al.

CIRCULATION (2009)

Article Respiratory System

First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension

F. Grimminger et al.

EUROPEAN RESPIRATORY JOURNAL (2009)

Review Biochemistry & Molecular Biology

Discovery of the nitric oxide signaling pathway and targets for drug development

Nathan S. Bryan et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2009)

Article Cardiac & Cardiovascular Systems

Role of guanylate cyclase modulators in decompensated heart failure

Veselin Mitrovic et al.

HEART FAILURE REVIEWS (2009)

Review Medicine, General & Internal

Pulmonary hypertension in chronic heart failure

D. Bonderman et al.

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2009)

Article Cardiac & Cardiovascular Systems

Diagnosis, Assessment, and Treatment of Non-Pulmonary Arterial Hypertension Pulmonary Hypertension

Marius M. Hoeper et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)

Article Cardiac & Cardiovascular Systems

Updated Evidence-Based Treatment Algorithm in Pulmonary Arterial Hypertension

Robyn J. Barst et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)

Article Cardiac & Cardiovascular Systems

Cellular and Molecular Basis of Pulmonary Arterial Hypertension

Nicholas W. Morrell et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)

Review Pharmacology & Pharmacy

Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics

Emily J. Tsai et al.

PHARMACOLOGY & THERAPEUTICS (2009)

Article Respiratory System

From arginine methylation to ADMA: A novel mechanism with therapeutic potential in chronic lung diseases

Dariusz Zakrzewicz et al.

BMC Pulmonary Medicine (2009)

Article Pharmacology & Pharmacy

Probing the presence of the ligand-binding haem in cellular nitric oxide receptors

B. Roy et al.

BRITISH JOURNAL OF PHARMACOLOGY (2008)

Article Pharmacology & Pharmacy

Dose-dependent beneficial hemodynamic effects of BAY 41-2272 in a canine model of acute pulmonary thromboembolism

Stefany B. A. Cau et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2008)

Article Respiratory System

Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension

R. T. Schermuly et al.

EUROPEAN RESPIRATORY JOURNAL (2008)

Review Biochemistry & Molecular Biology

Role of oxidative stress and nitric oxide in atherothrombosis

Edith Lubos et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2008)

Article Pharmacology & Pharmacy

Sustained soluble guanylate cyclase stimulation offsets nitric-oxide synthase inhibition to restore acute cardiac modulation by sildenafil

Takahiro Nagayama et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)

Article Critical Care Medicine

Inhaled agonists of soluble guanylate cyclase induce selective pulmonary vasodilation

Oleg V. Evgenov et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2007)

Review Medicine, General & Internal

Lessons from oncology to understand and treat pulmonary hypertension

S. Adnot et al.

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2007)

Article Cardiac & Cardiovascular Systems

Long-term use of sildenafil in the therapeutic management of heart failure

Marco Guazzi et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2007)

Review Pharmacology & Pharmacy

Impaired tissue responsiveness to organic nitrates and nitric oxide: A new therapeutic frontier?

Yuliy Y. Chirkov et al.

PHARMACOLOGY & THERAPEUTICS (2007)

Review Biotechnology & Applied Microbiology

Peroxynitrite: biochemistry, pathophysiology and development of therapeutics

Csaba Szabo et al.

NATURE REVIEWS DRUG DISCOVERY (2007)

Review Cardiac & Cardiovascular Systems

Phosphodiesterase regulation of nitric oxide signaling

David A. Kass et al.

CARDIOVASCULAR RESEARCH (2007)

Review Cardiac & Cardiovascular Systems

Inhaled NO as a therapeutic agent

Kenneth D. Bloch et al.

CARDIOVASCULAR RESEARCH (2007)

Article Peripheral Vascular Disease

Targeting heme-oxidized soluble guanylate cyclase in experimental heart failure

Guido Boerrigter et al.

HYPERTENSION (2007)

Review Physiology

Nitric oxide and peroxynitrite in health and disease

Pal Pacher et al.

PHYSIOLOGICAL REVIEWS (2007)

Article Pharmacology & Pharmacy

Significant pharmacokinetic and pharmacodynamic interaction of warfarin with the NO-independent sGC activator HMR1766

Heike Oberwittler et al.

JOURNAL OF CLINICAL PHARMACOLOGY (2007)

Article Pharmacology & Pharmacy

Effect of BAY 41-2272 in the pulmonary hypertension induced by heparin-protamine complex in anaesthetized dogs

Cristiane F. Freitas et al.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2007)

Article Medicine, General & Internal

Shattuck Lecture: Nitric oxide and cyclic GMP in cell signaling and drug development

Ferid Murad

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Article Pharmacology & Pharmacy

Acrylamide analog as a novel nitric oxide-independent soluble guanylyl cyclase activator

Masaki Nakane et al.

JOURNAL OF PHARMACOLOGICAL SCIENCES (2006)

Article Medicine, Research & Experimental

Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels

Johannes-Peter Stasch et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Review Medicine, General & Internal

Recent Advances in Understanding Endothelial Dysfunction in Atherosclerosis

Zhihong Yang et al.

CLINICAL MEDICINE & RESEARCH (2006)

Review Biotechnology & Applied Microbiology

NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential

Oleg V. Evgenov et al.

NATURE REVIEWS DRUG DISCOVERY (2006)

Article Physiology

Pulmonary vascular effects of nitric oxide-cGMP augmentation in a model of chronic pulmonary hypertension in fetal and neonatal sheep

P Deruelle et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2005)

Review Cardiac & Cardiovascular Systems

Explaining the phenomenon of nitrate tolerance

T Münzel et al.

CIRCULATION RESEARCH (2005)

Article Critical Care Medicine

Antiproliferative effects of phosphodiesterase type 5 inhibition in human pulmonary artery cells

J Wharton et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)

Article Cardiac & Cardiovascular Systems

Pathophysiology of coronary artery disease

P Libby et al.

CIRCULATION (2005)

Review Pharmacology & Pharmacy

Nitrosative stress and pharmacological modulation of heart failure

P Pacher et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2005)

Review Medicine, General & Internal

Mechanisms of disease - Inflammation, atherosclerosis, and coronary artery disease

GK Hansson

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Physiology

Effects of BAY 41-2272, a soluble guanylate cyclase activator, on pulmonary vascular reactivity in the ovine fetus

P Deruelle et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2005)

Article Cardiac & Cardiovascular Systems

Efficacy and optimal dose of sildenafil in primary pulmonary hypertension

A Chockalingam et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2005)

Article Multidisciplinary Sciences

Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment

A Ahluwalia et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Letter Cardiac & Cardiovascular Systems

Effects of the sGC stimulator BAY 41-2272 are not mediated by phosphodiesterase 5 inhibition

E Bischoff et al.

CIRCULATION (2004)

Article Urology & Nephrology

A comparative study of sildenafil, NCX-911 and BAY41-2272 on the anococcygeus muscle of diabetic rats

JS Kalsi et al.

INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH (2004)

Article Multidisciplinary Sciences

Reduced cGMP signaling associated with neointimal proliferation and vascular dysfunction in late-stage atherosclerosis

VO Melichar et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Medicine, General & Internal

Combination of isosorbide dinitrate and hydralazine in blacks with heart failure

AL Taylor et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)

Review Medicine, General & Internal

Mechanisms of disease: Pulmonary arterial hypertension

HW Farber et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)

Article Pharmacology & Pharmacy

Antiplatelet properties of a novel, non-NO-based soluble guanylate cyclase activator, BAY 41-2272

AJ Hobbs et al.

VASCULAR PHARMACOLOGY (2003)

Article Pharmacology & Pharmacy

Mechanisms of nitric oxide independent activation of soluble guanylyl cyclase

P Schmidt et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2003)

Article Medicine, Research & Experimental

A-350619: A novel activator of soluble guanylyl cyclase

LN Miller et al.

LIFE SCIENCES (2003)

Article Biochemistry & Molecular Biology

Inhibition of deactivation of NO-sensitive guanylyl cyclase accounts for the sensitizing effect of YC-1

M Russwurm et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

BAY 41-2272 activates two isoforms of nitric oxide-sensitive guanylyl cyclase

M Koglin et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)

Article Biochemistry & Molecular Biology

YC-1-mediated vascular protection through inhibition of smooth muscle cell proliferation and platelet function

DA Tulis et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)

Article Pharmacology & Pharmacy

Pharmacological actions of a novel NO-independent guanylyl cyclase stimulator, BAY 41-8543: in vitro studies

JP Stasch et al.

BRITISH JOURNAL OF PHARMACOLOGY (2002)

Article Pharmacology & Pharmacy

Cardiovascular actions of a novel NO-independent guanylyl cyclase stimulator, BAY 41-8543: in vivo studies

JP Stasch et al.

BRITISH JOURNAL OF PHARMACOLOGY (2002)

Article Chemistry, Medicinal

NO-independent stimulators of soluble guanylate cyclase

A Straub et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2001)

Article Multidisciplinary Sciences

NO-independent regulatory site on soluble guanylate cyclase

JP Stasch et al.

NATURE (2001)

Article Biochemistry & Molecular Biology

YC-1, a benzyl indazole derivative, stimulates vascular cGMP and inhibits neointima formation

DA Tulis et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)

Article Multidisciplinary Sciences

Human recombinant soluble guanylyl cyclase: Expression, purification, and regulation

YC Lee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)