Journal
CHROMOSOME RESEARCH
Volume 19, Issue 1, Pages 83-98Publisher
SPRINGER
DOI: 10.1007/s10577-010-9172-5
Keywords
binding models; FRAP; high mobility; transient chromatin binding; diffusion; transcription; DNA repair
Ask authors/readers for more resources
Fluorescent protein labelling, as well as impressive progress in live cell imaging have revolutionised the view on how essential nuclear functions like gene transcription regulation and DNA repair are organised. Here, we address questions like how DNA-interacting molecules find and bind their target sequences in the vast amount of DNA. In addition, we discuss methods that have been developed for quantitative analysis of data from fluorescence recovery after photobleaching experiments (FRAP).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available