Journal
CHROMOSOME RESEARCH
Volume 16, Issue 6, Pages 827-837Publisher
SPRINGER
DOI: 10.1007/s10577-008-1229-3
Keywords
cytogenetic map; FISH; gene; human comparison; river buffalo
Funding
- Campania Region LR5 [DG.RSTL.083.001]
- National Research Council of Rome [DG.RSTL.083.002]
Ask authors/readers for more resources
We report an extended river buffalo (Bubalus bubalis, 2n=50; BBU) cytogenetic map including 388 loci, of which 68 have been FISH-mapped on autosomes in the present study. Ovine and caprine BAC clones containing both type I loci (known genes) and type II loci (simple sequence repeats (SRs), microsatellite marker, sequence-tagged sites (STSs)), previously assigned to sheep chromosomes, have been localized on R-banded river buffalo chromosomes (BBU), which expands the cytogenetic map of this important domestic species and increases our knowledge of the physical organization of its genome. The loci mapped in the present study correspond to loci already localized on homoeologous cattle (and sheep) chromosomes and chromosome bands, further confirming the high degree of chromosome homoeologies among bovids. The comparison of the integrated cytogenetic maps of BBU2p/BBU10 and BBU5p/BBU16 with those of human chromosomes (HSA) 6 and 11, respectively, identified, at least, nine conserved chromosome segments in each case and complex rearrangements differentiating river buffalo (and cattle) and human chromosomes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available