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CENP-A: the key player behind centromere identity, propagation, and kinetochore assembly

Journal

CHROMOSOMA
Volume 121, Issue 6, Pages 527-538

Publisher

SPRINGER
DOI: 10.1007/s00412-012-0386-5

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Funding

  1. Canadian Institutes of Health Research [MOP-106548]
  2. Canadian Cancer Society Research Institute [700824]

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Chromosome segregation is the one of the great problems in biology with complexities spanning from biophysics and polymer dynamics to epigenetics. Here, we summarize the current knowledge and highlight gaps in understanding of the mechanisms controlling epigenetic regulation of chromosome segregation.

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