Journal
CHROMATOGRAPHIA
Volume 69, Issue -, Pages S23-S32Publisher
SPRINGER HEIDELBERG
DOI: 10.1365/s10337-009-0956-8
Keywords
Column liquid chromatography; Gas chromatography; Mass spectrometry; Metabonomics; Metabolomics; Metabolic profiling analysis
Funding
- National Natural Science Foundation of China [20775078, 20675082, 30571783]
- National Basic Research Program [2007CB707802, 2007CB109201]
- National Key Technologies RD Program [2006BAK02A 12]
- State Ministry of Science and Technology of China
- Chinese Academy of Sciences [K2006A13]
- German Federal Ministry of Education and Research (BMBF)
Ask authors/readers for more resources
The widespread availability, suitability, and high sensitivity of chromatogrophy-mass spectrometry for chemical profiling analysis of multi-component biosamples are demonstrated by the comprehensive analysis of metabolites in all kind of biofluids or tissue and cell extracts. This review provides an overview of current chromatographic-mass spectrometric metabonomic methods and applications. The focus is on the description of global metabolic profiling techniques as well as on additional important aspects of metabonomics research such as sample pretreatment and information mining methods including strategies for the identification of potential biomarkers.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
