Journal
CHIRALITY
Volume 26, Issue 12, Pages 801-805Publisher
WILEY-BLACKWELL
DOI: 10.1002/chir.22358
Keywords
cinchona alkaloid derivatives; asymmetric; anti-Mannich reaction; anti-3; 3-disubstituted 2-oxindole
Funding
- National Natural Science Foundation of China [21102055]
- Natural Science Foundation of Jilin province [201015237]
Ask authors/readers for more resources
A series of cinchona alkaloid derivatives were used to catalyze the asymmetric anti-Mannich-type reaction of 3-methyl-2-oxindole with N-tosyl aryl aldimines. The resulting anti-3,3-disubstituted 2-oxindole products were obtained in good yields (up to 92%) with high diastereo- and enantioselectivities (anti/syn up to 97:3 and 91% ee). Chirality 26:801-805, 2014. (c) 2014 Wiley Periodicals, Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
