4.3 Article

Improved Chiral SFC Screening for Analytical Method Development

Journal

CHIRALITY
Volume 25, Issue 11, Pages 799-804

Publisher

WILEY-BLACKWELL
DOI: 10.1002/chir.22218

Keywords

SFC; chiral screening; method development; fast analysis

Funding

  1. MRL New Technologies Review & Licensing Committee (NT-RLC)

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In this study we describe the evaluation of a recently developed supercritical fluid chromatography (SFC) instrument for automated chiral SFC method development. The greatly improved gradient dwell volume and liquid flow control of the new instrument in combination with the use of shorter columns containing smaller stationary phase particles affords chiral SFC method development that is faster and more universal than previous systems. Chirality 25:799-804, 2013. (c) 2013 Wiley Periodicals, Inc.

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