Journal
CHINESE SCIENCE BULLETIN
Volume 58, Issue 13, Pages 1473-1482Publisher
SCIENCE PRESS
DOI: 10.1007/s11434-013-5788-0
Keywords
polymer; single; nanochannels; biosensors; ion track-etching
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Funding
- National Basic Research Program of China [2011CB935700]
- National Natural Science Foundation of China [21201170, 11290163, 21121001, 91127025, 21171171]
- Chinese Academy of Sciences [KJZD-EW-M01]
- Beijing National Laboratory for Molecular Sciences [CMS-PY-201243]
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There are many elaborate masterpieces exist in natural world. Learning from nature, people developed serial intelligent biomimetic devices. Biomimetic smart nanochannels received widespread attention for mimicking biological processes in bodies. Excellent stability, tailorable surface characteristics and nano-size effects rend polymer single nanochannel an ideal candidate for constructing sensitive and reproducible biosensors. Nanochannels are responsive for special analytes while appropriate recognition elements are modified in channels wall. In this review, we summarized recent works in contructing biosensors that are using polymer single nanochannels for detecting various analytes.
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