Journal
CHINESE SCIENCE BULLETIN
Volume 57, Issue 14, Pages 1612-1615Publisher
SCIENCE PRESS
DOI: 10.1007/s11434-011-4744-0
Keywords
pyridone; ytterbium chloride; tandem reaction; catalysis; synthesis
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Funding
- National Natural Science Foundation of China [20872106, 20972107]
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An efficient method was developed for the synthesis of arylidene heterobicyclic 3-cyano-2-pyridones via ytterbium chloride catalyzed tandem condensation of aromatic aldehydes, cyclic ketones, and cyanoacetamide. The conditions and scope of the reaction were investigated and a reaction mechanism was proposed.
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