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Amplification of the entire kanamycin biosynthetic gene cluster during empirical strain improvement of Streptomyces kanamyceticus
Koji Yanai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Biosynthetic pathway for mannopeptimycins, lipoglycopeptide antibiotics active against drug-resistant gram-positive pathogens
Nathan A. Magarvey et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)
The lipopeptide antibiotic A54145 biosynthetic gene cluster from Streptomyces fradiae
V Miao et al.
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2006)
In vitro 'sexual' evolution through the PCR-based staggered extension process (StEP)
Huimin Zhao et al.
NATURE PROTOCOLS (2006)
Intraspecific variability of the terminal inverted repeats of the linear chromosome of Streptomyces ambofaciens
Frederic Choulet et al.
JOURNAL OF BACTERIOLOGY (2006)
Identification of tailoring genes involved in the modification of the polyketide backbone of rifamycin B by Amycolatopsis mediterranei S699
J Xu et al.
MICROBIOLOGY-SGM (2005)
Transcriptional control by A-factor of strR, the pathway-specific transcriptional activator for streptomycin biosynthesis in Streptomyces griseus
A Tomono et al.
JOURNAL OF BACTERIOLOGY (2005)
Daptomycin biosynthesis in Streptomyces roseosporus:: cloning and analysis of the gene cluster and revision of peptide stereochemistry
V Miao et al.
MICROBIOLOGY-SGM (2005)
Spectinomycin resistance in rpsE mutants is recessive in Streptomyces roseosporus
XW He et al.
JOURNAL OF ANTIBIOTICS (2005)
Involvement of AlpV, a new member of the Streptomyces antibiotic regulatory protein family, in regulation of the duplicated type II polyketide synthase alp gene cluster in Streptomyces ambofaciens
B Aigle et al.
JOURNAL OF BACTERIOLOGY (2005)
Molecular cloning, sequence analysis, and heterologous expression of the phosphinothricin tripeptide biosynthetic gene cluster from Streptomyces viridochromogenes DSM 40736
JAV Blodgett et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Identification of PimR as a positive regulator of pimaricin biosynthesis in Streptomyces natalensis
N Antón et al.
JOURNAL OF BACTERIOLOGY (2004)
In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis
ON Sekurova et al.
JOURNAL OF BACTERIOLOGY (2004)
Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome
XH Pang et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)
Identification of a phosphopantetheinyl transferase for erythromycin biosynthesis in Saccharopolyspora erythraea
KJ Weissman et al.
CHEMBIOCHEM (2004)
Positive control of tylosin biosynthesis: pivotal role of TylR
G Stratigopoulos et al.
MOLECULAR MICROBIOLOGY (2004)
Reverse engineering of industrial pharmaceutical-producing actinomycete strains using DNA microarrays
AM Lum et al.
METABOLIC ENGINEERING (2004)
Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus
M Sosio et al.
MICROBIOLOGY-SGM (2004)
Organizational and mutational analysis of a complete FR-008/candicidin gene cluster encoding a structurally related polyene complex
S Chen et al.
CHEMISTRY & BIOLOGY (2003)
Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization
M Oliynyk et al.
MOLECULAR MICROBIOLOGY (2003)
The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by Nonomuraea species
M Sosio et al.
CHEMISTRY & BIOLOGY (2003)
Use of the rpoB gene to determine the specificity of base substitution mutations on the Escherichia coli chromosome
L Garibyan et al.
DNA REPAIR (2003)
Assembling the glycopeptide antibiotic scaffold:: The biosynthesis of A47934 from Streptomyces toyocaensis NRRL 15009
J Pootoolal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Genome shuffling leads to rapid phenotypic improvement in bacteria
YX Zhang et al.
NATURE (2002)
Organization of biosynthetic gene cluster for avermectin in Streptomyces avermitilis:: analysis of enzymatic domains in four polyketide synthases
H Ikeda et al.
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2001)
Amphotericin biosynthesis in Streptomyces nodosus:: deductions from analysis of polyketide synthase and late genes
P Caffrey et al.
CHEMISTRY & BIOLOGY (2001)
Cloning and characterization of a phosphopantetheinyl transferase from Streptomyces verticillus ATCC15003, the producer of the hybrid peptide-polyketide antitumor drug bleomycin
C Sánchez et al.
CHEMISTRY & BIOLOGY (2001)
Cloning and functional analysis of a phosphopantetheinyl transferase superfamily gene associated with jadomycin biosynthesis in Streptomyces venezuelae ISP5230
LR Wang et al.
MICROBIOLOGY-SGM (2001)
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa
C Waldron et al.
CHEMISTRY & BIOLOGY (2001)
Genetic methods and strategies for secondary metabolite yield improvement in actinomycetes
RH Baltz
ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY (2001)
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis
JF Aparicio et al.
CHEMISTRY & BIOLOGY (2000)
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455:: analysis of the gene cluster and deduction of the biosynthetic pathway
T Brautaset et al.
CHEMISTRY & BIOLOGY (2000)