Journal
CHINESE PHYSICS B
Volume 20, Issue 5, Pages -Publisher
IOP PUBLISHING LTD
DOI: 10.1088/1674-1056/20/5/058504
Keywords
graphene nanoribbon; nanopores; DNA sequencing; first-principles
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Funding
- Ministry of Science and Technology of China [2011CB921900]
- China Postdoctoral Science Foundation [20090460145, 201003009]
- Fundamental Research Funds for the Central Universities of China [201012200053]
- Science and Technology Program of Hunan Province of China [2010DFJ411]
- Science Development Foundation of Central South University, China [08SDF02, 09SDF09]
- High Performance Computing Center of CSU
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A biosensor device, built from graphene nanoribbons (GNRs) with nanopores, was designed and studied by first-principles quantum transport simulation. We have demonstrated the intrinsic transport properties of the device and the effect of different nucleobases on device properties when they are located in the nanopores of GNRs. It was found that the device's current changes remarkably with the species of nucleobases, which originates from their different chemical compositions and coupling strengths with GNRs. In addition, our first-principles results clearly reveal that the distinguished ability of a device's current depends on the position of the pore to some extent. These results may present a new way to read off the nucleobases sequence of a single-stranded DNA (ssDNA) molecule by such GNRs-based device with designed nanopores
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