Journal
CHINESE JOURNAL OF ORGANIC CHEMISTRY
Volume 33, Issue 2, Pages 224-244Publisher
SCIENCE PRESS
DOI: 10.6023/cjoc201208036
Keywords
tetrazole; antihypertensive; antibacterial; antiviral; herbicide; energetic materials; catalyst
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Funding
- National Natural Science Foundation of China [21172181]
- Research Fellowship for International Young Scientists from International (Regional) Cooperation and Exchange Program [81250110089]
- Key Program from Natural Science Foundation of Chongqing City [CSTC2012jjB10026]
- Specialized Research Fund for the Doctoral Program of Higher Education of China [SRFDP 20110182110007]
- Fundamental Research Funds for the Central Universities [XDJK2011D007, XDJK2012B026]
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Tetrazole is an important five-membered aromatic heterocycle with poly-nitrogen electron-rich planar structural feature. This unique structure endows tetrazole derivatives as drugs, explosives, functional materials etc. to exhibit wide potential applications in medicinal, agrochemical, material science and so on. Relevant researches have been becoming active and some important achievements have been made. Based our work on azoles and referring to other literature in recent 5 years, this review systematically summarized the recent advances in the synthesis of tetrazole compounds and their application researches as medicinal drugs, agrochemicals and materials.
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