Journal
CHINESE JOURNAL OF CHEMISTRY
Volume 32, Issue 8, Pages 694-698Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.201400186
Keywords
Michael addition-Lactonization; dihydrobenzofuran; Fc-PIP
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A highly enantioselective intramolecular Michael addition-Lactonization domino reaction of a range of enon acids catalyzed by nuleophilic organocatalyst (Fc-PIP) was developed, furnishing cis-2,3-dihydrobenzofuran derivatives with excellent enantioselecitivities (94%-98% ee) and good diastereoselectivities (up to 99/1).
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