4.5 Article

Iron(III)-Catalyzed Direct N-Alkylation of Azoles via Oxidative Transformation of sp3 C-H Bonds under Solvent-Free Conditions

Journal

CHINESE JOURNAL OF CHEMISTRY
Volume 30, Issue 10, Pages 2285-2291

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.201200690

Keywords

azoles; N-alkylation; solvent-free; iron catalyst; C?H activation

Funding

  1. Scientific Research Foundation of the State Education Ministry [107108]
  2. National Natural Science Foundation of China [J0730425]

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A new approach to synthesize N-alkylation of azoles by iron(III)-catalyst under solvent-free conditions was developed. The method is broad in scope and highly efficient.

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