Journal
CHINESE JOURNAL OF CHEMISTRY
Volume 30, Issue 5, Pages 1075-1082Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.201100560
Keywords
palladium; copper-catalyst; microwave; isoquinolines; tandem reaction; coupling cyclization
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Funding
- National Natural Science Foundation of China [21002038]
- CCNU from the Colleges' Basic Research and Operation of MOE [CCNU09A01014]
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A novel three-component reaction of o-bromobenzaldehyde, terminal alkynes and tert-butyl amine has been established, which proceeded smoothly to give 3-substituted isoquinolines in good yields in the presence of palladium/copper catalysts under microwave irradiation.
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