4.5 Article

Kinetic Resolution of Aryl Alkenylcarbinols Catalyzed by Fc-PIP

Journal

CHINESE JOURNAL OF CHEMISTRY
Volume 30, Issue 6, Pages 1289-1294

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.201200410

Keywords

kinetic resolution; acyl transfer; Fc-PIP

Funding

  1. Fundamental Research Funds for the Central Universities
  2. Natural Science Foundation of China [20972047, 21172068]
  3. 'Shu Guang' project of Shanghai Municipal Education Commission
  4. Shanghai Education Development Foundation [09SG28]
  5. Shanghai Committee of Science and Technology [11DZ2260600]

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An effective kinetic resolution of a variety of aryl alkenylcarbinols catalyzed by nonenzymatic acyl transfer catalyst Fc-PIP was developed, affording corresponding unreacted alcohols in good to excellent ee value up to 99% and with selectivity factors up to 24.

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