Journal
CHINESE JOURNAL OF CHEMISTRY
Volume 28, Issue 3, Pages 480-482Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.201090100
Keywords
one-pot; FeCl3; trimethyl silyl cyanide; alpha-aminonitriles
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alpha-Amino nitriles are synthesized by the three-component coupling reaction of aldehydes, amines and trimethyl-silyl cyanide using FeCl3 as a solid acid catalyst, under solvent-free conditions in good yields. The catalyst was recovered by simple filtration and was recycled in subsequent reactions.
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