4.5 Article

Application of Heteropolyacids as Heterogeneous and Recyclable Catalysts for One-Pot Synthesis of 3-Cyanopyridine Derivatives

Journal

CHINESE JOURNAL OF CHEMISTRY
Volume 27, Issue 3, Pages 569-572

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.200990093

Keywords

3-cyanopyridine; one-pot; heteropolyacid; recyclable; 3,4-dimethoxy acetophenone

Funding

  1. Azzahra University Research Council

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A simple, clean and environmentally benign route to the synthesis of 3-cyanopyridines is described via a one-pot multi-component reaction of 3,4-dimethoxyacetophenone, malonitrile or ethylcyanoacetate, aldehyde and ammonium acetate using heteropolyacids as heterogeneous and recyclable catalysts in very good yields.

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