Selective voltammetric determination of uric acid in the presence of ascorbic acid at ordered mesoporous carbon modified electrodes

A novel chemically modified electrode was fabricated by immobilizing ordered mesoporous carbon (OMC) onto a glassy carbon (GC) electrode. The electrocatalytic behavior of the OMC modified electrode towards the oxidation of uric acid (UA) and ascorbic acid (AA) was studied. Compared to a glassy carbon electrode, the OMC modified electrode showed a faster electron transfer rate and reduced the overpotentials greatly. Furthermore, the OMC modified electrode resolved the overlapping voltammetric responses of UA and AA into two well-defined voltammetric peaks with peak separation of ca. 0.38 V. All results show that the OMC modified electrode has a good electrocatalytic ability to UA and AA, and has an excellent response towards UA even in the presence of high concentration AA.