4.7 Article

The novel usage of thiourea nitrate in aryl nitration

Journal

CHINESE CHEMICAL LETTERS
Volume 25, Issue 1, Pages 87-89

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2013.09.003

Keywords

Thiourea nitrate; Nitration; Thiourea; Aromatic compounds

Funding

  1. Fundamental Research Funds for the Central Universities
  2. Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry, PR China

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Thiourea nitrate (TN) was easily prepared from thiourea and nitric acid to explore its use as a new nitration reagent. Nitrations of various aromatic compounds utilizing TN in concentrated sulfuric acid were studied. TN could convert aromatic compounds to the corresponding nitrated derivatives with various abnormal yields under mild conditions. The results suggested that the reaction mechanism might be different from those of traditional nitration reagents. (C) 2013 Juan Shi. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

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