Journal
CHINESE CHEMICAL LETTERS
Volume 22, Issue 4, Pages 427-430Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2010.10.038
Keywords
2,3-Dihydro-4(1H)-quinazolinone; 2-Anthranilamide; Aldehydes; Ketones; Synthesis in water
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2-Substituted-2,3-dihydro-4(1H)-quinazolinones were synthesized in high yield by condensation of 2-anthranilamide with aromatic aldehydes or ketones in refluxing water without catalyst. This protocol has advantages of high yield, simple work-up and environmental friendly procedure. (C) 2010 Min Wang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
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