Journal
CHINESE CHEMICAL LETTERS
Volume 21, Issue 1, Pages 47-50Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2009.07.018
Keywords
Reductive amination; Silica chloride; Solvent-free conditions; Sodium borohydride
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Funding
- Research Council of Mazandaran University
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A simple and convenient procedure for the preparation of amines from aldehydes and ketones with sodium borohydride activated by silica chloride as a catalyst under solvent-free conditions is described. A variety of aliphatic and aromatic aldehydes, ketones and amines when mixed with NaBH4/Silica chloride at room temperature, afforded excellent yield of the corresponding amines. (C) 2009 Heshmatollah Alinezhad. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
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