4.7 Article

Wet cyanuric chloride promoted efficient synthesis of amidoalkyl naphthols under solvent-free conditions

Journal

CHINESE CHEMICAL LETTERS
Volume 20, Issue 4, Pages 383-386

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2008.12.018

Keywords

One-pot; Cyanuric chloride; Catalyst; Amidoalkyl naphthol; Multicomponent

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An efficient and direct procedure has been developed for the preparation of amidoalkyl naphthols by a one-pot condensation of aryl aldehydes, 2-naphthol and urea or amides, in the presence of wet-cyanuric chloride (wet-TCT) as a catalyst. The reactions were carried out under solvent-free media. The present methodology offers several advantages such as excellent yields, simple procedure and eco-friendly reaction condition. (C) 2008 Gholam Hossein Mahdavinia. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

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