Journal
CHINESE CHEMICAL LETTERS
Volume 20, Issue 5, Pages 542-544Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2008.12.011
Keywords
7-Azaindirubin; Synthesis; Antitumor activity
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Twenty 7-azaindirubin derivatives were designed and synthesized. Their antitumor activities were evaluated in vitro against DU145 cell line. The pharmacological results showed that most of the prepared compounds displayed the excellent activity. Compound 18 exhibited the most potent antitumor activity among the tested compounds. (C) 2008 Qi Zheng Yao. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
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