A novel application of horseradish peroxidase: Oxidation of alcohol ethoxylate to alkylether carboxylic acid

A novel application of horseradish peroxidase (HRP) in the oxidation of alcohol ethoxylate to alkylether carboxylic acid in the present of H(2)O(2) was reported in this paper. We propose the mechanism for the catalytic oxidation reaction is that the hydrogen transfers from the substrate to the ferryl oxygen to form the alpha-hydroxy carbon radical intermediate. The reaction offers a new approach for further research structure and catalytic mechanism of HRP and production of alkylether carboxylic acid. (c) 2008 Li Fei Zhi. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.